Is the information provided by amino acid PET radiopharmaceuticals clinically equivalent in gliomas?

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Clinical impact of amino acid PET in gliomas.

With an incidence of 20.5 per 100,000 people each year, tumors of the central nervous system are a heterogeneous group, with meningiomas (35.5%) and gliomas (30%) being the most common (1). Although 97% of meningiomas are benign, 54% of gliomas are highly malignant glioblastomas of World Health Organization (WHO) grade IV. Survival rates are 35.7% at 1 y and 4%–7% at 5 y for glioblastoma, 60%–8...

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PET Radiopharmaceuticals

PET (positron emission tomography) is a powerful imaging technique that can provide quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (PET radiopharmaceuticals) in the body. Positrons (ß+) are positively charged beta particles. They are emitted when the atom is proton rich. A positron has only a transient existence. After losing all of its kinetic ene...

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PET Radiopharmaceuticals

PET (Positron Emission Tomography) is a powerful imaging technique through which quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (PET radiopharmaceuticals) in the body can be realized. Positrons (β +) are positively charged beta particles. They are emitted when the atom is proton enriched. A positron has only a transient existence. After losing all ...

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The clinical management of adults with low-grade gliomas (LGGs) remains a challenge. There is no curative treatment, and management of individual patients is a matter of deciding optimal timing as well as right treatment modality. In addition to conventional imaging techniques, positron emission tomography (PET) with amino acid tracers can facilitate diagnostic and therapeutic procedures. In th...

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ژورنال

عنوان ژورنال: European Journal of Nuclear Medicine and Molecular Imaging

سال: 2017

ISSN: 1619-7070,1619-7089

DOI: 10.1007/s00259-017-3710-8